Emerging Severe and Fatal Infections Due to Klebsiella pneumoniae in Two University Hospitals in France
Emerging Severe and Fatal Infections Due to Klebsiella pneumoniae in Two University Hospitals in France
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DOI：
10.1128/jcm.00676-11
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发表时间：
2011-08-01
影响因子：
9.4
通讯作者：
Arlet, Guillaume
中科院分区：
文献类型：
--
作者：
Decre, Dominique;Verdet, Charlotte;Arlet, Guillaume
在过去的几十年里，东南亚国家报告了由高粘性肺炎克雷伯氏菌引起的严重感染。这份报告显示了它们在法国的出现，在两所大学医院的两年时间里观察到了12例病例。K2型的两个克隆(序列型86[ST86]和ST380)导致了5例快速致死性菌血症病例，其中3例与肺炎有关，7例肝脓肿病例是由ST23的K1菌株引起的。
Severe infections caused by hypermucoviscous Klebsiella pneumoniae have been reported in Southeast Asian countries over the past several decades. This report shows their emergence in France, with 12 cases observed during a 2-year period in two university hospitals. Two clones (sequence type 86 [ST86] and ST380) of serotype K2 caused five rapidly fatal bacteremia cases, three of which were associated with pneumonia, whereas seven liver abscess cases were caused by K1 strains of ST23.