Expression zones of three novel genes abut the developing anterior neural plate of Xenopus embryo
Expression zones of three novel genes abut the developing anterior neural plate of Xenopus embryo
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DOI：
10.1016/s1567-133x(02)00077-7
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发表时间：
2003-05-01
影响因子：
1.2
通讯作者：
Zaraisky, AG
中科院分区：
文献类型：
--
作者：
Novoselov, VV;Alexandrova, EM;Zaraisky, AG
我们确定了三个新的基因，非洲爪蟾早期神经胚的前非神经外胚层内表达。这些基因的表达被观察到在不同的领域互补的同源结构域基因Xanf-1在前神经板的表达区。这些基因之一，Ras样GTP酶Ras-dva，标志着前基板外胚层区域;第二，Agr家族同源基因，XAgr 2，在最前外胚层的水泥腺原基中表达，第三，新的基因Nlo在外侧神经褶皱中表达。这些基因在发育中的胶浆和孵化腺原基中瞬时表达，在成熟的胶浆和孵化腺中被抑制。XAgr 2和Nlo也在耳泡中表达，Ras-dva在神经管的背外侧柱中表达。(C)出版社：Elsevier Science B. V.
We identified three novel genes that were expressed within the anterior non-neural ectoderm of Xenopus early neurula embryos. The expression of these genes was observed in the different areas complementary to the expression zone of a homeodomain gene Xanf-1 in the anterior neural plate. One of these genes, a Ras-like GTP-ase Ras-dva, marked the anterior placodal ectoderm area; a second, an Agr family homologous gene, XAgr2, was expressed in the anterior-most ectoderm in the cement gland primordium, and a third, novel gene Nlo was expressed in the lateral neural folds. The genes were transiently expressed in the developing cement and hatching gland primordia, and repressed in the mature cement and hatching glands. XAgr2 and Nlo were also expressed in the otic vesicles, and Ras-dva was expressed in the dorso-lateral column of the neural tube. (C) 2003 Published by Elsevier Science B.V.