Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection?
Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection?
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DOI：
10.1002/jmv.26114
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发表时间：
2020-06-09
影响因子：
12.7
通讯作者：
Liu, Xuefeng
中科院分区：
文献类型：
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作者：
Kang, Hanyujie;Wang, Yishan;Liu, Xuefeng
据报道，“康复”的冠状病毒病-19（COVID-19）对严重急性呼吸综合征相关冠状病毒-2（SARS-CoV-2）的“复测阳性”，并对这种新型冠状病毒和COVID-19疾病提出了几个重要问题。在这篇评论中，我们讨论了几个问题：（a）SARS-CoV-2能否重新感染从COVID-19中康复的个体？这个问题也与其他问题有关：SARS-CoV-2感染是否诱导保护性反应或中和抗体？SARS-CoV-2疫苗有效吗？(b)为什么一些COVID-19康复患者重新检测SARS-CoV-2 RNA呈阳性？(c)一些重新检测SARS-CoV-2 RNA阳性的COVID-19患者是否具有传染性？及（d）应如何管理SARS-CoV-2复检呈阳性的COVID-19患者？
"Retest Positive" for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) from "recovered" coronavirus disease-19 (COVID-19) has been reported and raised several important questions for this novel coronavirus and COVID-19 disease. In this commentary, we discussed several questions: (a) Can SARS-CoV-2 re-infect the individuals who recovered from COVID-19? This question is also associated with other questions: whether or not SARS-CoV-2 infection induces protective reaction or neutralized antibody? Will SARS-CoV-2 vaccines work? (b) Why could some recovered patients with COVID-19 be re-tested positive for SARS-CoV-2 RNA? (c) Are some recovered pwith atients COVID-19 with re-testing positive for SARS-CoV-2 RNA infectious? and (d) How should the COVID-19 patients with retest positive for SARS-CoV-2 be managed?