Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males.
Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males.
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DOI：
10.1007/s00394-015-1016-9
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发表时间：
2016-09
影响因子：
5
通讯作者：
Spencer JP
中科院分区：
文献类型：
--
作者：
Alharbi MH;Lamport DJ;Dodd GF;Saunders C;Harkness L;Butler LT;Spencer JP
流行病学证据表明，长期食用水果类黄酮与认知益处有关;然而，富含类黄酮（FR）饮料对餐后即刻认知功能的急性影响需要检查。目的是调查是否消费FR橙子汁与急性认知的好处超过6小时的健康中年人。年龄在30-65岁之间的男性以随机、双盲、平衡的顺序在2天内饮用240 ml FR橙子汁（272 mg）和卡路里匹配的安慰剂，间隔2周洗脱期。在基线（饮酒前）和饮酒后2小时和6小时评估认知功能和主观情绪。认知成套测验包括八项单独的认知测验。在基线测量之前食用标准化早餐，并在饮酒后3小时食用标准化午餐。从基线分析的变化显示，执行功能和精神速度测试的表现显着更好的FR饮料相比，安慰剂。客观认知功能的影响得到了FR饮料相对于安慰剂对主观警觉性的显著益处的支持。这些数据表明，FR橙子汁的消费可以在6小时的过程中，在健康的中年人的客观和主观认知急剧提高。
Epidemiological evidence suggests that chronic consumption of fruit-based flavonoids is associated with cognitive benefits; however, the acute effects of flavonoid-rich (FR) drinks on cognitive function in the immediate postprandial period require examination. The objective was to investigate whether consumption of FR orange juice is associated with acute cognitive benefits over 6 h in healthy middle-aged adults. Males aged 30–65 consumed a 240-ml FR orange juice (272 mg) and a calorie-matched placebo in a randomized, double-blind, counterbalanced order on 2 days separated by a 2-week washout. Cognitive function and subjective mood were assessed at baseline (prior to drink consumption) and 2 and 6 h post consumption. The cognitive battery included eight individual cognitive tests. A standardized breakfast was consumed prior to the baseline measures, and a standardized lunch was consumed 3 h post-drink consumption. Change from baseline analysis revealed that performance on tests of executive function and psychomotor speed was significantly better following the FR drink compared to the placebo. The effects of objective cognitive function were supported by significant benefits for subjective alertness following the FR drink relative to the placebo. These data demonstrate that consumption of FR orange juice can acutely enhance objective and subjective cognition over the course of 6 h in healthy middle-aged adults.
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影响因子：
4.1
作者：
Scholey, Andrew B.;French, Stephen J.;Haskell, Crystal F.
通讯作者：
Haskell, Crystal F.
影响因子：
3.3
作者：
Hendrickson SJ;Mattes RD
通讯作者：
Mattes RD
影响因子：
3.7
作者：
Rendeiro C;Vauzour D;Rattray M;Waffo-Téguo P;Mérillon JM;Butler LT;Williams CM;Spencer JP
通讯作者：
Spencer JP
影响因子：
2.9
作者：
Field, David T.;Williams, Claire M.;Butler, Laurie T.
通讯作者：
Butler, Laurie T.
影响因子：
4.7
作者：
Manach, C;Morand, C;Rémésy, C
通讯作者：
Rémésy, C