DEGOS DISEASE - ASSOCIATION WITH ANTICARDIOLIPIN ANTIBODIES AND THE LUPUS ANTICOAGULANT
DEGOS DISEASE - ASSOCIATION WITH ANTICARDIOLIPIN ANTIBODIES AND THE LUPUS ANTICOAGULANT
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DOI：
10.1136/bmj.289.6445.576
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发表时间：
1984-01-01
影响因子：
--
通讯作者：
HUGHES, GRV
中科院分区：
文献类型：
--
作者：
ENGLERT, HJ;HAWKES, CH;HUGHES, GRV
一名妇女提出了多个脑血栓和皮肤病变的特点德戈斯病。她的血清中含有高滴度的抗心磷脂抗体，并显示狼疮抗凝活性，这两种抗体都是系统性红斑狼疮血栓形成倾向的强烈标志物。这一发现可能对这种通常致命的疾病有治疗意义。
A woman presented with multiple cerebral thromboses and skin lesions characteristic of Degos' disease. Her serum contained high titres of anticardiolipin antibodies and showed lupus anticoagulant activity, both known to be strong markers of a thrombotic tendency in systemic lupus erythematosus. This finding may have therapeutic implications for this usually fatal disease.