Serum antimullerian hormone levels are independently related to miscarriage rates after in vitro fertilization-embryo transfer
Serum antimullerian hormone levels are independently related to miscarriage rates after in vitro fertilization-embryo transfer
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DOI：
10.1016/j.fertnstert.2017.07.001
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发表时间：
2017-09-01
影响因子：
6.7
通讯作者：
Fanchin, Renato
中科院分区：
文献类型：
--
作者：
Tarasconi, Bruno;Tadros, Teddy;Fanchin, Renato
Objective: To investigate whether serum antimullerian hormone (AMH) levels are independently related to miscarriage rates after in vitro fertilization-embryo transfer (IVF-ET).Design: Cohort study.Setting: University-affiliated IVF-ET center.Patient(s): A total of 1,060 patients who attained a clinical pregnancy after IVF-ET.Interventions(s): Centralized serum AMH measurements were performed within the 12 months before IVF-ET. Binary logistic regression was used to verify whether serum AMH levels were associated with the occurrence of a miscarriage independently from confounding factors, such as age and intensity of ovarian response to controlled ovarian stimulation assessed by the number of oocytes retrieved.Main Outcome Measure(s): Miscarriage rates.Result(s): In patients displaying reduced serum AMH levels, miscarriage rates were significantly increased independently from age and the number of oocytes retrieved.Conclusion(s): The present data indicate that serum AMH levels are independently associated with the occurrence of a miscarriage after IVF-ET. (C) 2017 by American Society for Reproductive Medicine.
