In-situ generation of Et3SiBr from BiBr3 and Et3SiH and its use in preparation of dialkyl ethers
In-situ generation of Et3SiBr from BiBr3 and Et3SiH and its use in preparation of dialkyl ethers
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DOI：
10.1016/s0040-4039(02)01532-0
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发表时间：
2002-09-16
影响因子：
1.8
通讯作者：
Blacklock, TJ
中科院分区：
文献类型：
--
作者：
Bajwa, JS;Jiang, XL;Blacklock, TJ
报道的BiBr3-Et3SiH催化硅基醚与羰基化合物的还原醚化反应被原位形成的et3sir催化，并通过独立使用商业试剂进行了验证。由于Et3SiBr对水分敏感并且不易获得，因此仍然建议将这种原位生成方法作为选择方法。利用这种方法，几种醇在非常温和的条件下通过它们的硅基中间体，如TES、TBDMS和TIPS转化为二烷基醚。(C) 2002 Elsevier Science Ltd.版权所有。
The reported BiBr3-Et3SiH catalyzed reductive etherifications of silyl ethers with carbonyl compounds are shown to be catalyzed by the in situ formed Et3SiBr and verified by an independent use of the commercial reagent. As Et3SiBr is moisture sensitive and is not readily available, this in situ generation is still recommended as the method of choice. Utilizing this method, several alcohols were transformed under very mild conditions into dialkyl ethers via their silyl intermediates, such as TES, TBDMS, and TIPS. (C) 2002 Elsevier Science Ltd. All rights reserved.