Penile Cancer

Penile Cancer
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DOI:
10.1007/978-3-030-52021-2_25
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发表时间:
2020-09
期刊:
Chemotherapy and Immunotherapy in Urologic Oncology
影响因子:
--
通讯作者:
J. Mark;D. Squadrito
J. Mark;D. Squadrito
中科院分区:
其他
文献类型:
--
作者:
J. Mark;D. Squadrito

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阴茎癌是一种罕见的男性生殖器恶性肿瘤,主要由鳞状细胞癌组成。高风险原发性肿瘤通常转移至区域淋巴结,需要积极的治疗以预防与该疾病相关的某些发病率和死亡率。化疗、靶向治疗和免疫疗法用于治疗的各个阶段,通常与具有治愈目的的可测量疾病的手术切除相结合。发生远处转移的患者的生存率非常低,在这种情况下的全身治疗是姑息性的。
Penile cancer is a rare malignancy of the male genitalia composed primarily of squamous cell carcinoma. High-risk primary tumors often metastasize to regional lymph nodes which require aggressive management to prevent the certain morbidity and mortality associated with this disease. Chemotherapy, targeted therapy, and immunotherapy are used in various stages of treatment, often in combination with surgical resection of measurable disease with curative intent. Patients with distant metastases have very poor survival, and systemic therapy in this setting is palliative.