CHANNELING OF AMMONIA FROM GLUTAMINASE TO CARBAMOYL-PHOSPHATE SYNTHETASE IN LIVER-MITOCHONDRIA
CHANNELING OF AMMONIA FROM GLUTAMINASE TO CARBAMOYL-PHOSPHATE SYNTHETASE IN LIVER-MITOCHONDRIA
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DOI：
10.1016/0014-5793(85)80018-1
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发表时间：
1985-01-01
期刊：
影响因子：
3.5
通讯作者：
MEIJER, AJ
中科院分区：
文献类型：
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作者：
MEIJER, AJ
在离体大鼠肝线粒体中，谷氨酰胺合成瓜氨酸的速率对线粒体外液中氨浓度的变化没有反应。这表明，线粒体中通过转氨酶产生的氨直接被引导到氨甲酰磷酸合成酶。
In isolated rat‐liver mitochondria the rate of citrulline synthesis from glutamine does not respond to changes in the ammonia concentration in the extramitochondrial fluid. This suggest that ammonia, produced in the mitochondria via glutaminase, is directly channeled to carbamoyl‐phosphate synthetase.