A phase I study of veliparib (ABT-888) in combination with weekly carboplatin and paclitaxel in advanced solid malignancies and enriched for triple-negative breast cancer (TNBC).
A phase I study of veliparib (ABT-888) in combination with weekly carboplatin and paclitaxel in advanced solid malignancies and enriched for triple-negative breast cancer (TNBC).
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veliparib (ABT-888) 联合每周一次卡铂和紫杉醇治疗晚期实体恶性肿瘤和丰富的三阴性乳腺癌 (TNBC) 的 I 期研究。
DOI:
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发表时间:
2015
期刊:
影响因子:
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通讯作者:
S. Puhalla
中科院分区:
文献类型:
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作者:
S. Pahuja;J. Beumer;L. Appleman;H. Tawbi;R. Stoller;James J. Lee;Yan Lin;Fei Ding;Jing Yu;C. Belani;A. Chen;V. Giranda;S. Shepherd;E. Chu;S. Puhalla
1015 Background: Veliparib (ABT-888) is an oral, potent small molecule inhibitor of poly-ADP-ribose polymerase (PARP). The combination of veliparib (V) with carboplatin (C) and paclitaxel (P) dosed...