On the role of endogenous opioid peptides: failure of naloxone to influence shock escape threshold in the rat.
On the role of endogenous opioid peptides: failure of naloxone to influence shock escape threshold in the rat.
复制标题
内源性阿片肽的作用：纳洛酮未能影响大鼠的休克逃逸阈值。
DOI：
10.1016/0024-3205(76)90339-8
复制
发表时间：
1976
期刊：
影响因子：
6.1
通讯作者：
F. Larsen
中科院分区：
文献类型：
--
作者：
A. Goldstein;G. T. Pryor;Leon S. Otis;F. Larsen
用足以阻断吗啡镇痛的纳洛酮剂量处理的大鼠，其逃避足电击的阈值没有变化。数据不支持内源性阿片调节疼痛和不适反应的假设。
Rats treated with doses of naloxone sufficient to block morphine analgesia showed no change in the threshold for escape from foot shock. The data offer no support to the hypothesis that an endogenous opioid modulates responsiveness to pain and discomfort.