Steroid control of muscle remodeling during metamorphosis in Manduca sexta.
Steroid control of muscle remodeling during metamorphosis in Manduca sexta.
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烟草天蛾变态过程中类固醇对肌肉重塑的控制。
DOI:
10.1002/(sici)1097-4695(199604)29:4
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发表时间:
1996
期刊:
影响因子:
--
通讯作者:
Truman,JW
中科院分区:
文献类型:
--
作者:
Hegstrom,CD;Truman,JW
During metamorphosis in the tobacco hornworm,Manduca sexta,the abdominal body‐wall muscle DEO1 is remodeled to form the adult muscle DE5. The degeneration of muscle DEO1 involves the dismantling of its contractile apparatus followed by the degeneration of muscle nuclei. As some nuclei are degenerating, others begin to incorporate 5‐bromodeoxyuridine (BrdU), indicating the onset of nuclear proliferation. This proliferation is initially most evident at the site where the motoneuron contacts the muscle remnant. The developmental events involved in muscle remodeling are under the control of the steroid hormones, the ecdysteroids. The loss of the contractile elements of the larval muscle requires the rise and fall of the prepupal peak of ecdysteroids, whereas the subsequent loss of muscle nuclei is influenced by the slight rise in ecdysteroids seen after pupal ecdysis. Incorporation of BrdU by muscle nuclei depends on both the adult peak of the ecdysteroids and contact with the motoneuron. Unilateral axotomy blocks proliferation within the rudiment, but it does not block its subsequent differentiation into a very thin muscle in the adult. © 1996 John Wiley & Sons, Inc.
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影响因子:
5.3
作者:
R. Levine;J. Truman
通讯作者:
J. Truman
DOI:
--
发表时间:
1968
期刊:
影响因子:
--
作者:
H. Nüesch
通讯作者:
H. Nüesch
影响因子:
7.8
作者:
Toselli, P A;Pepe, F A
通讯作者:
Pepe, F A
影响因子:
2.2
作者:
A. Crossley
通讯作者:
A. Crossley
影响因子:
--
作者:
S. Kopeć
通讯作者:
S. Kopeć