Defining Ethnic and Racial Differences in Osteoporosis and Fragility Fractures
Defining Ethnic and Racial Differences in Osteoporosis and Fragility Fractures
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DOI：
10.1007/s11999-011-1863-5
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发表时间：
2011-07-01
影响因子：
4.2
通讯作者：
Cauley, Jane A.
中科院分区：
文献类型：
--
作者：
Cauley, Jane A.
骨质疏松性骨折是一个重大的公共卫生问题。文献表明骨折的发生率因种族和民族而异，我的目的是回顾目前有关种族和民族对以下方面影响的文献：（1）骨折的流行病学;（2）骨质疏松症的骨密度患病率;（3）骨质疏松性髋部骨折的后果;（4）骨折风险的差异;（5）骨质疏松症的筛查、诊断和治疗的差异。选择性地回顾了与骨质疏松症、种族和人种有关的现有文献。种族和人种，如性别，影响骨折的流行病学，白色女性的骨折率最高。非洲裔美国人的骨密度较高;然而，这些女性更有可能在髋部骨折后死亡，住院时间更长，出院时不太可能走动。不同种族骨折的一致危险因素包括年龄较大、骨密度较低、既往骨折史和两次或两次以上福尔斯跌倒史。在骨质疏松症的筛查、诊断和治疗方面存在种族和民族差异。在不同种族和民族中，骨折的女性多于1年内发生乳腺癌、心肌梗死和冠心病死亡的女性人数之和。预防工作应针对所有妇女，不论其种族/族裔，特别是如果她们有多种风险因素。
Osteoporotic fractures are a major public health issue. The literature suggests there are variations in occurrence of fractures by ethnicity and race.My purpose is to review current literature related to the influence of ethnicity and race on the (1) epidemiology of fracture; (2) prevalence of osteoporosis by bone mineral density; (3) consequences of osteoporotic hip fracture; (4) differences in risk fracture for fracture; and (5) disparities in screening, diagnosis, and treatment of osteoporosis.Current literature was selectively reviewed related to osteoporosis, ethnicity, and race.Ethnicity and race, like sex, influence the epidemiology of fractures, with highest fracture rates in white women. Bone mineral density is higher in African Americans; however, these women are more likely to die after hip fracture, have longer hospital stays, and are less likely to be ambulatory at discharge. Consistent risk factors for fracture across ethnicity include older age, lower bone mineral density, previous history of fracture, and history of two or more falls. Ethnic and racial disparities exist in the screening, diagnosis, and treatment of osteoporosis.Across ethnic and racial groups, more women experience fractures than the combined number of women who experience breast cancer, myocardial infarction, and coronary death in 1 year. Prevention efforts should target all women, irrespective of their race/ethnicity, especially if they have multiple risk factors.