Carbonyl Desaturation: Where Does Catalysis Stand?
Carbonyl Desaturation: Where Does Catalysis Stand?
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DOI：
10.1021/acscatal.0c04712
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发表时间：
2021-01-05
期刊：
影响因子：
12.9
通讯作者：
Baran, Phil S.
中科院分区：
文献类型：
--
作者：
Gnaim, Samer;Vantourout, Julien C.;Baran, Phil S.
从战略和战术Vantage来看，简单的醇氧化和羰基去饱和之间有很强的相似性。由于它们都试图从有机基质中提取氢，因此它们是在过去70多年来通过化学计量方法解决的看似简单的转变。在过去的十年里，人们对这两种简单反应的催化作用越来越感兴趣。在这个角度来看，从过去5年的最新进展突出了过渡金属催化和无金属的羰基去饱和的方法。通过历史回顾和对每一个新发展的详细研究，我们试图解决一个问题，即在什么样的背景下，催化战略成为理想的。
There is a strong parallel between simple alcohol oxidation and carbonyl desaturation from both strategic and tactical vantage points. As they both seek to extract hydrogen from an organic substrate, they are deceptively simple looking transformations that have been addressed over the past 70+ years through stoichiometric means. The past decade has seen an intensifying level of interest in rendering both of these simple reactions catalytic. In this Perspective, recent advances from the past 5 years are highlighted featuring both transition-metal-catalyzed and metal-free approaches to carbonyl desaturation. Through a historical overview and a detailed look at each of these new developments, we seek to address the question of in what context a catalytic strategy emerges as ideal.