Regional reductions of gray matter volume in familial dyslexia
Regional reductions of gray matter volume in familial dyslexia
复制标题
DOI：
10.1212/01.wnl.0000134673.95020.ee
复制
发表时间：
2004-08-24
期刊：
影响因子：
9.9
通讯作者：
Perani, D
中科院分区：
文献类型：
--
作者：
Brambati, SM;Termine, C;Perani, D
采用一种优化的基于体素的形态计量学方法，对一组家族性阅读障碍个体进行了灰质体积的活体解剖学研究。在双侧颞平面、颞叶下皮质和小脑核团观察到灰质体积的局灶性异常，这表明潜在的解剖异常可能是这些受试者书面语言习得缺陷的原因。
An in vivo anatomic study of gray matter volume was performed in a group of familial dyslexic individuals, using an optimized method of voxel-based morphometry. Focal abnormalities in gray matter volume were observed bilaterally in the planum temporale, inferior temporal cortex, and cerebellar nuclei, suggesting that the underlying anatomic abnormalities may be responsible for defective written language acquisition in these subjects.