A new route to highly functionalized heterocyclic rings

A new route to highly functionalized heterocyclic rings
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DOI:
10.1021/jo062305n
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发表时间:
2007-02-16
影响因子:
3.6
通讯作者:
Board, Johnathan
Board, Johnathan
中科院分区:
化学2区
文献类型:
--
作者:
Parsons, Philip J.;Waters, Alexander J.;Board, Johnathan

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[图]一种新颖的级联反应已被开发用于快速构建杂环。环化是热诱导的并且不涉及金属离子的使用。这种高效的呋喃结构是在针对抗生素乳霉素 1 合成的研究中开发出来的。
[GRAPHIC]A novel cascade reaction has been developed for the rapid construction of heterocyclic rings. The cyclization is thermally induced and does not involve the use of metal ions. This highly efficient construction of furans has been developed during studies directed toward the synthesis of the antibiotic lactonamycin 1.