Systemic vascular function is associated with muscular power in older adults.
Systemic vascular function is associated with muscular power in older adults.
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DOI：
10.1155/2012/386387
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发表时间：
2012
影响因子：
4.7
通讯作者：
Fielding RA
中科院分区：
文献类型：
--
作者：
Heffernan KS;Chalé A;Hau C;Cloutier GJ;Phillips EM;Warner P;Nickerson H;Reid KF;Kuvin JT;Fielding RA
肌肉力量和肌肉力量的丧失是老年人身体功能丧失和残疾进展的关键决定因素。在这项研究中，我们研究了老年人全身血管功能与肌肉力量和力量的相关性。血管内皮功能指标包括肱动脉血流介导的舒张功能（FMD）和脉搏波振幅反应性充血指数（PWA-RHI）。增强指数（AIx）作为与动脉硬度和波反射相关的全身血管功能的量度。肌肉力量的措施包括一个重复最大值（1 RM）的双边腿部压力。峰值肌肉力量在5个重复期间进行尽可能快的双侧腿部压力在40%1RM。肌力与肱FMD（r = 0.43，P < 0.05）、PWA-RHI（r = 0.42，P < 0.05）和AIx（r =-0.54，P < 0.05）相关。肌肉力量与任何血管功能指标无关。总之，全身血管功能与下肢肌肉力量有关，但与老年人的肌肉力量无关。随着年龄的增长，肌肉力量的丧失是否会导致全身血管功能失调或血管功能障碍导致肌肉力量的下降仍有待确定。
Age-associated loss of muscular strength and muscular power is a critical determinant of loss of physical function and progression to disability in older adults. In this study, we examined the association of systemic vascular function and measures of muscle strength and power in older adults. Measures of vascular endothelial function included brachial artery flow-mediated dilation (FMD) and the pulse wave amplitude reactive hyperemia index (PWA-RHI). Augmentation index (AIx) was taken as a measure of systemic vascular function related to arterial stiffness and wave reflection. Measures of muscular strength included one repetition maximum (1RM) for a bilateral leg press. Peak muscular power was measured during 5 repetitions performed as fast as possible for bilateral leg press at 40% 1RM. Muscular power was associated with brachial FMD (r = 0.43, P < 0.05), PWA-RHI (r = 0.42, P < 0.05), and AIx (r = −0.54, P < 0.05). Muscular strength was not associated with any measure of vascular function. In conclusion, systemic vascular function is associated with lower-limb muscular power but not muscular strength in older adults. Whether loss of muscular power with aging contributes to systemic vascular deconditioning or vascular dysfunction contributes to decrements in muscular power remains to be determined.