Cell-in-cell structures are involved in the competition between cells in human tumors.
Cell-in-cell structures are involved in the competition between cells in human tumors.
复制标题
细胞内结构参与人类肿瘤细胞之间的竞争
DOI：
10.1080/23723556.2014.1002707
复制
发表时间：
2015-10
影响因子：
2.1
通讯作者：
Overholtzer M
中科院分区：
文献类型：
--
作者：
Sun Q;Huang H;Overholtzer M
吞噬活细胞可能代表了细胞死亡的一种机制。我们报道了E-钙粘蛋白(上皮钙粘蛋白)在人类癌细胞中的表达有助于细胞内结构的形成，这种机制被称为齿状突，并且齿状突有助于异质癌细胞群体中一种形式的细胞竞争。
The engulfment of live cells may represent a mechanism of cell death. We reported that E-cadherin (epithelial cadherin) expression in human cancer cells favors the formation of cell-in-cell structures through the mechanism known as entosis, and that entosis contributes to a form of cellular competition in heterogeneous cancer cell populations.