Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin

Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin
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DOI:
10.1177/0269881115609019
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发表时间:
2015-11-01
影响因子:
4.1
通讯作者:
Griffiths, Roland R.
Griffiths, Roland R.
中科院分区:
医学3区
文献类型:
--
作者:
Barrett, Frederick S.;Johnson, Matthew W.;Griffiths, Roland R.

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修订后的 30 项神秘体验问卷 (MEQ30) 是之前在一项针对含裸盖菇素蘑菇引起的神秘体验的在线调查中开发的。被评定的经历平均发生在问卷完成前八年。当前的论文使用裸盖菇素受控剂量的实验研究数据验证了 MEQ30。汇总并分析了五项实验室实验的数据,其中参与者 (n=184) 接受了中等到高口服剂量的裸盖菇素(至少 20 毫克/70 公斤)。验证性因素分析的结果证明了 MEQ30 的可靠性和内部效度。结构方程模型通过显示 MEQ30 的潜在变量分数积极预测归因于裸盖菇素体验的态度、行为和幸福感的持续变化,同时控制参与者评定的药物效应强度的贡献,证明了 MEQ30 的外部和收敛有效性。这些发现支持使用 MEQ30 作为个人神秘体验的有效衡量标准。 MEQ30 验证了以前版本的神秘体验问卷中使用的完整神秘体验评分方法,并提供了 MEQ30 的独立版本以供未来研究使用。
The 30-item revised Mystical Experience Questionnaire (MEQ30) was previously developed within an online survey of mystical-type experiences occasioned by psilocybin-containing mushrooms. The rated experiences occurred on average eight years before completion of the questionnaire. The current paper validates the MEQ30 using data from experimental studies with controlled doses of psilocybin. Data were pooled and analyzed from five laboratory experiments in which participants (n=184) received a moderate to high oral dose of psilocybin (at least 20 mg/70 kg). Results of confirmatory factor analysis demonstrate the reliability and internal validity of the MEQ30. Structural equation models demonstrate the external and convergent validity of the MEQ30 by showing that latent variable scores on the MEQ30 positively predict persisting change in attitudes, behavior, and well-being attributed to experiences with psilocybin while controlling for the contribution of the participant-rated intensity of drug effects. These findings support the use of the MEQ30 as an efficient measure of individual mystical experiences. A method to score a complete mystical experience that was used in previous versions of the mystical experience questionnaire is validated in the MEQ30, and a stand-alone version of the MEQ30 is provided for use in future research.