Three-Dimensional Computed Tomographic Analysis of Airway Anatomy in Patients With Obstructive Sleep Apnea
Three-Dimensional Computed Tomographic Analysis of Airway Anatomy in Patients With Obstructive Sleep Apnea
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DOI：
10.1016/j.joms.2009.09.087
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发表时间：
2010-02-01
影响因子：
1.9
通讯作者：
Kaban, Leonard
中科院分区：
文献类型：
--
作者：
Abramson, Zachary;Susarla, Srinivas;Kaban, Leonard
目的：识别气道大小和形状的异常，与阻塞性睡眠呼吸暂停（OSA）的存在和严重程度相关。材料和方法：这是一个回顾性的病例系列的患者进行治疗的OSA谁有术前计算机断层扫描（CT）扫描的上气道。同期行CT检查的非气道病变患者作为对照组。进行数字化三维CT重建，分析12个气道大小参数和4个气道形态参数。在OSA患者的头颅侧位片上测量后气道间隙、中气道间隙和舌骨到下颌平面的距离。双变量分析用于确定与呼吸紊乱指数（RDI）测量的OSA的存在和严重程度相关的因素。结果：44例OSA患者中，有15例（男10例，女5例）术前、术后均有CT检查。另外，17例患者（11例男性和6例女性）用作对照。阻塞性睡眠呼吸暂停（OSA）患者气道长度明显增加（P
Purpose: To identify abnormalities in airway size and shape that correlate with the presence and severity of obstructive sleep apnea (OSA).Materials and Methods: This was a retrospective case series of patients undergoing treatment of OSA who had preoperative computed tomographic (CT) scans of the upper airway available. Patients who had undergone CT scanning for nonairway pathologic features during the same period served as the controls. Digital 3D-CT reconstructions were made and 12 parameters of airway size and 4 of shape were analyzed. The posterior airway space, middle airway space, and hyoid to mandibular plane distance were measured on the lateral cephalograms of the patients with OSA. Bivariate analysis was used to identify the factors associated with the presence and severity of OSA as measured by the respiratory disturbance index (RDI). Multiple regression analysis identified the factors that correlated with the RDI.Results: Of the 44 patients with OSA, 15 (10 men and 5 women) had pre- and postoperative CT scans available. In addition, 17 patients (11 men and 6 women) were used as controls. The airway length was significantly increased in the patients with OSA (P