Mobile Application Interventions and Weight Loss in Type 2 Diabetes: A Meta-Analysis

Mobile Application Interventions and Weight Loss in Type 2 Diabetes: A Meta-Analysis
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DOI:
10.1002/oby.22715
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发表时间:
2020-03-01
期刊:
影响因子:
6.9
通讯作者:
Li, Mingzi
Li, Mingzi
中科院分区:
医学2区
文献类型:
--
作者:
Cai, Xue;Qiu, Shanhu;Li, Mingzi

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目的本荟萃分析旨在评估移动的应用程序(app)干预对2型糖尿病患者体重减轻的影响。方法检索电子数据库中的随机对照试验,检查使用移动的app干预对体重减轻的效果,通过体重或其他指标(如BMI或腰围)进行评估。应用随机效应模型获得体重平均差异和95%CI。结果纳入了14项研究,招募了2,129名2型糖尿病患者。移动的应用程序干预可显著降低体重(体重平均差异,-0.84 kg; 95% CI:-1.51至-0.17 kg)和降低腰围(-1.35 cm; 95% CI:-2.16至-0.55 cm),但可能不会降低BMI(-0.08 kg/m(2); 95% CI:-0.41至0.25 kg/m(2))。在肥胖患者或使用移动的应用程序干预结合其他行为成分的研究中,这种减少似乎更为明显。然而,体重减轻不受移动的应用程序功能(所有P-交互> 0.05)或干预持续时间(所有P > 0.87)的调节。结论移动的应用程序干预导致2型糖尿病患者体重减轻,值得推荐用于减肥推广。
Objective This meta-analysis aimed to assess the effect of mobile application (app) interventions on weight loss in patients with type 2 diabetes.Methods Electronic databases were searched for randomized controlled trials examining the use of mobile app interventions with outcomes on weight loss evaluated by body weight or other measures such as BMI or waist circumference. A random-effects model was applied to obtain weight mean differences and 95% CIs.Results Fourteen studies enrolling 2,129 patients with type 2 diabetes were included. Mobile app interventions could significantly reduce body weight (weight mean difference, -0.84 kg; 95% CI: -1.51 to -0.17 kg) and lower waist circumference (-1.35 cm; 95% CI: -2.16 to -0.55 cm) but may not decrease BMI (-0.08 kg/m(2); 95% CI: -0.41 to 0.25 kg/m(2)). The reductions appeared to be more pronounced in patients with obesity or among studies using mobile app interventions combined with other behavior components. However, weight loss was not moderated by the functionalities of the mobile apps (all P-interaction > 0.05) or by the intervention duration (all P > 0.87).Conclusions Mobile app interventions lead to weight loss in patients with type 2 diabetes and are worth recommending for weight loss promotion.