Solubility of Bovine-Derived Hydroxyapatite by Solid Titration, pH 3.5-5
Solubility of Bovine-Derived Hydroxyapatite by Solid Titration, pH 3.5-5
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DOI：
10.1021/cg900070v
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发表时间：
2009-06-01
影响因子：
3.8
通讯作者：
Darvell, Brian W.
中科院分区：
文献类型：
--
作者：
Chen Zhuofan;Huang Baoxin;Darvell, Brian W.
牛源性羟基磷灰石（BDHA）通常用于治疗牙槽骨缺损。在文献中缺乏关于其体内降解速率的一致性，并且对其体外溶解度知之甚少，这与磷酸钙生物材料的一般降解机制有关。因此，本研究利用已建立的固体滴定法测定BDHA的有效溶解度等温线，并确定平衡固相。
Bovine-derived hydroxyapatite (BDHA) is commonly used in treating alveolar bony defects. There is lack of agreement in the literature as to its rate of degradation in vivo, and little is known about its solubility in vitro, which is relevant to the mechanism of degradation of calcium phosphate biomaterials in general. Therefore, this study was undertaken to measure the effective solubility isotherm of BDHA using the established solid-titration method and to identify the equilibrium solid phase.