Pressure drops for droplet flows in microfluidic channels
Pressure drops for droplet flows in microfluidic channels
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DOI：
10.1088/0960-1317/16/8/010
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发表时间：
2006-08-01
影响因子：
2.3
通讯作者：
Velankar, Sachin S.
中科院分区：
文献类型：
--
作者：
Adzima, Brian J.;Velankar, Sachin S.
设计芯片上的微流体泵需要知道跨装置的压降对流体流速的依赖性。对于两相液滴型流动的情况，这种关系可能是复杂的。我们的特点是在矩形截面的微流体通道中的油中的水滴的单列流的流量-压力关系。这种液滴流的压力总是比连续相的相应单相流的压力大-有时超过50%。尽管水滴具有比连续相油低得多的粘度。发现超压与相对于通道尺寸的液滴尺寸相当好地相关。这种相关性的超压，以及这里提出的微通道中的液滴的大小的相关性，应该提供方便的指导方针，在设计微流体装置的两相流。
Designing on-chip microfluidic pumps requires that the dependence of pressure drop across the device on the fluid flow rate be known. This relationship can be complicated for the case of two-phase droplet type flows. We characterized the flow-pressure relationship for the single-file flow of water drops in oil in microfluidic channels of rectangular cross sections. The pressure for such droplet flows was always larger - sometimes over 50% larger - than that for corresponding single-phase flows of the continuous phase. This is in spite of the fact that the water drops had a substantially lower viscosity than the continuous phase oil. The excess pressure was found to correlate reasonably well with the size of the drops relative to the size of the channels. This correlation for the excess pressure, as well as a correlation presented here for the size of drops in microchannels, should provide convenient guidelines in designing microfluidic devices for two-phase flows.