Investigating the effects of tic suppression on premonitory urge ratings in children and adolescents with Tourette's syndrome
Investigating the effects of tic suppression on premonitory urge ratings in children and adolescents with Tourette's syndrome
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DOI：
10.1016/j.brat.2007.08.007
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发表时间：
2007-12-01
影响因子：
4.1
通讯作者：
Rice, Kevin A.
中科院分区：
文献类型：
--
作者：
Himle, Michael B.;Woods, Douglas W.;Rice, Kevin A.
抽搐代表了一类复杂的行为，具有神经生物学起源，并受到个体内外因素的影响。最近引起注意的一个因素是先兆冲动。当代的行为模型表明，某些联系之前存在着厌恶性的躯体冲动，当抽搐受到抑制时，这种冲动的严重程度会增加，并因抽搐的表现而减弱。有人提出，消除先兆冲动可能会通过负强化来加强或维持抽搐。这项研究是第一个经验性地评估抽搐抑制对先兆冲动现象的影响。5名8-17岁的儿童和青少年参与了这项研究。使用ABAB反转设计，在自由抽动基线（BL）和强化抽动抑制（零率行为的差异强化）条件下记录抽动频率和主观先兆冲动评级。结果显示，5名儿童中有4名表现出可靠的抑制。四个孩子谁实现了抑制，三个表现出的模式，其中主观冲动评级较高，在抑制期间比BL。研究结果为部分儿童抽动功能的负强化观点提供了初步支持。(C)2007爱思唯尔有限公司保留所有权利。
Tics represent a complex class of behaviors that have a neurobiological origin and are influenced by factors both internal and external to the individual. One factor that has gained recent attention is the premonitory urge. Contemporary behavioral models suggest that some ties are preceded by aversive somatic urges that increase in severity when tics are suppressed and are attenuated by performance of the tic. It has been proposed that the removal of premonitory urges may strengthen or maintain tics via negative reinforcement. This investigation is the first to empirically evaluate the effect of tic suppression on the premonitory urge phenomenon. Five children and adolescents, ages 8-17 years, participated in the study. Using an ABAB reversal design, tic frequency and subjective premonitory urge ratings were recorded under conditions of free-to-tic baseline (BL) and reinforced tic suppression (differential reinforcement of zero-rate behavior). Results show that four of the five children demonstrated reliable suppression. Of the four children who achieved suppression, three demonstrated a pattern in which subjective urge ratings were higher during suppression than during BL. Results provide preliminary support for the negative reinforcement view of tic function for some children. (C) 2007 Elsevier Ltd. All rights reserved.