UCSC Genome Browser enters 20th year

UCSC Genome Browser enters 20th year
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DOI:
10.1093/nar/gkz1012
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发表时间:
2020-01-08
影响因子:
14.9
通讯作者:
Kent, W. James
Kent, W. James
中科院分区:
生物学2区
文献类型:
--
作者:
Lee, Christopher M.;Barber, Galt P.;Kent, W. James

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加州大学圣克鲁斯大学基因组浏览器网站(https://genome.ucsc.edu))向研究界提供高质量的基因组数据可视化和基因组注释进入第20个年头。在过去的一年里,我们在我们的网络BLAT工具中增加了一个新的选项,允许对所有基因组进行搜索,一个单细胞表达查看器(https://cells.ucsc.edu),),一个用于高密度变异数据的“棒棒糖”曲线图显示模式,一个用于数据提取的RESTful API,以及一个定制轨迹备份功能。新的数据集包括Tabula Muris单细胞表达数据、GeneHancer调控注释、癌症基因组图谱、泛癌变体、基因组参考联盟补丁序列、新的ENCODE转录因子结合位点峰和簇、基因组变体金标准变体数据库、基因组主宰变体和三个新的多物种比对跟踪。
The University of California Santa Cruz Genome Browser website (https://genome.ucsc.edu) enters its 20th year of providing high-quality genomics data visualization and genome annotations to the research community. In the past year, we have added a new option to our web BLAT tool that allows search against all genomes, a single-cell expression viewer (https://cells.ucsc.edu), a 'lollipop' plot display mode for high-density variation data, a RESTful API for data extraction and a custom-track backup feature. New datasets include Tabula Muris single-cell expression data, GeneHancer regulatory annotations, The Cancer Genome Atlas Pan-Cancer variants, Genome Reference Consortium Patch sequences, new ENCODE transcription factor binding site peaks and clusters, the Database of Genomic Variants Gold Standard Variants, Genomenon Mastermind variants and three new multi-species alignment tracks.