Meat-type chickens have a higher efficiency of mitochondrial oxidative phosphorylation than laying-type chickens
Meat-type chickens have a higher efficiency of mitochondrial oxidative phosphorylation than laying-type chickens
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DOI：
10.1016/j.cbpa.2011.01.020
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发表时间：
2011-05-01
影响因子：
2.3
通讯作者：
Amo, Taku
中科院分区：
文献类型：
--
作者：
Toyomizu, Masaaki;Kikusato, Motoi;Amo, Taku
肉用型鸡饲料利用率高，生长速度快。为了阐明饲料转化效率的类型特异性差异是否涉及线粒体生物能量学，模块动力学分析应用于骨骼肌线粒体的氧化磷酸化的两种类型的鸡。肉食型鸡骨骼肌线粒体的底物氧化和磷酸化活性高于产蛋型鸡，而质子漏较产蛋型鸡少，氧化磷酸化效率较高。解偶联蛋白（avUCP）基因的表达量和蛋白质含量低于产蛋型鸡，而腺嘌呤核苷酸转位酶（avANT）基因的表达量不高于产蛋型鸡。目前关于氧化磷酸化效率和UCP含量较高的研究结果可能部分支持肉食型鸡的高饲料效率。(C)2011 Elsevier Inc. All rights reserved.
Meat-type chickens show high feed efficiency and have a very rapid growth rate compared with laying-type chickens. To clarify whether the type-specific difference in feed conversion efficiency is involved in mitochondrial bioenergetics, modular kinetic analysis was applied to oxidative phosphorylation in skeletal muscle mitochondria of both type chickens. Mitochondria from skeletal muscle of meat-type chickens showed greater substrate oxidation and phosphorylating activities, and less proton leak than those of the laying-type, resulting in a higher efficiency of oxidative phosphorylation. Gene expression and protein content of uncoupling protein (avUCP) but not adenine nucleotide translocase (avANT) gene expression were lower in skeletal muscle mitochondria of meat-type chickens than the laying-type. The current results regarding a higher efficiency of oxidative phosphorylation and UCP content may partially support the high feed efficiency of meat-type chickens. (C) 2011 Elsevier Inc. All rights reserved.