High Acceleration Three-Dimensional T1-Weighted Dual Echo Dixon Hepatobiliary Phase Imaging Using Compressed Sensing-Sensitivity Encoding: Comparison of Image Quality and Solid Lesion Detectability with the Standard T1-Weighted Sequence
High Acceleration Three-Dimensional T1-Weighted Dual Echo Dixon Hepatobiliary Phase Imaging Using Compressed Sensing-Sensitivity Encoding: Comparison of Image Quality and Solid Lesion Detectability with the Standard T1-Weighted Sequence
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DOI：
10.3348/kjr.2018.0310
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发表时间：
2019-03-01
影响因子：
4.8
通讯作者：
Doneva, Mariya
中科院分区：
文献类型：
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作者：
Nam, Ju Gang;Lee, Jeong Min;Doneva, Mariya
目的：比较使用组合压缩感知（CS）-灵敏度编码（SENSE）方法的高加速度三维（30）T1加权梯度回波（GRE）序列与使用SENSE的传统3D GRE序列在钆塞酸增强肝脏MRI肝胆期（HBP）的图像质量和实性局灶性肝脏病变（FLL）的可检测性。材料和方法：共217例在3 T下进行钆塞酸增强肝脏MRI的患者（初步研究中54例，主研究中163例）被回顾性纳入。在主研究中，使用标准mDixon-3D-GRE技术和SENSE（加速因子[AF]：2.8，标准mDixon-GRE）以及使用组合CS-SENSE技术（CS-SENSE mDixon-GRE）的高加速mDixon-3D GRE技术进行两次HBP成像。两名腹部放射科医生一致评估了两个MRI数据集的图像质量。另外三名腹部放射科医生独立评估了每个数据集的诊断性能及其检测117例患者193个实体结节的实体FLL的能力，并使用折刀替代自由响应接收器操作特征（JAFROC）进行比较。与标准mDixon-GRE相比，CS-SENSE mDixon-GRE显示出更高的图像噪声，但运动伪影水平更低（所有p < 0.05）。在病变检测方面，使用JAFROC估计的阅片者平均优值对于标准mDixon-GRE为0.918，对于CS-SENSE mDixon-GRE为0.953（p = 0.142）。证实了CS-SENSE mDixon-GRE与标准mDixon-GRE相比的非劣效性（差异：0.064 [-0.012，0.081]）。结论：与标准mDixon-GRE序列相比，CS-SENSE mDixon-GRE HBP序列提供了相当的整体图像质量和非劣效的实体FFL可检测性，并缩短了采集时间。
Objective: To compare a high acceleration three-dimensional (30) T1-weighted gradient-recalled-echo (GRE) sequence using the combined compressed sensing (CS)-sensitivity encoding (SENSE) method with a conventional 3D GRE sequence using SENSE, with respect to image quality and detectability of solid focal liver lesions (FLLs) in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced liver MRI.Materials and Methods: A total of 217 patients with gadoxetic acid-enhanced liver MRI at 3T (54 in the preliminary study and 163 in the main study) were retrospectively included. In the main study, HBP imaging was done twice using the standard mDixon-3D-GRE technique with SENSE (acceleration factor [AF]: 2.8, standard mDixon-GRE) and the high acceleration mDixon-3D GRE technique using the combined CS-SENSE technique (CS-SENSE mDixon-GRE). Two abdominal radiologists assessed the two MRI data sets for image quality in consensus. Three other abdominal radiologists independently assessed the diagnostic performance of each data set and its ability to detect solid FLLs in 117 patients with 193 solid nodules and compared them using jackknife alternative free-response receiver operating characteristics (JAFROC).Results: There was no significant difference in the overall image quality. CS-SENSE mDixon-GRE showed higher image noise, but lesser motion artifact levels compared with the standard mDixon-GRE (all p < 0.05). In terms of lesion detection, reader-averaged figures-of-merit estimated with JAFROC was 0.918 for standard mDixon-GRE, and 0.953 for CS-SENSE mDixon-GRE (p = 0.142). The non-inferiority of CS-SENSE mDixon-GRE over standard mDixon-GRE was confirmed (difference: 0.064 [-0.012, 0.081]).Conclusion: The CS-SENSE mDixon-GRE HBP sequence provided comparable overall image quality and non-inferior solid FFL detectability compared with the standard mDixon-GRE sequence, with reduced acquisition time.