Whole-Brain Perfusion Measurement Using 320-Detector Row Computed Tomography in Patients With Cerebrovascular Steno-Occlusive Disease: Comparison With 15O-Positron Emission Tomography
Whole-Brain Perfusion Measurement Using 320-Detector Row Computed Tomography in Patients With Cerebrovascular Steno-Occlusive Disease: Comparison With 15O-Positron Emission Tomography
复制标题
DOI：
10.1097/rct.0b013e3181ebd16a
复制
发表时间：
2010-11-01
影响因子：
1.3
通讯作者：
Kinoshita, Toshibumi
中科院分区：
文献类型：
--
作者：
Shinohara, Yuki;Ibaraki, Masanobu;Kinoshita, Toshibumi
目的：320排CT动态扫描可为全脑CT灌注图提供连续的血管造影图像。通过与O-15正电子发射计算机断层扫描(PET-CBF)的对比，探讨320排CT扫描CTP脑血流量(CTP-CBF)的可靠性。方法：对10例单侧慢性狭窄闭塞症患者进行全脑CTP和PET检查。结果：虽然CTP-CBF值平均比PET-CBF值低约30%，但两者的平均缺血/非缺血脑血流量比值基本相同(P=0.804)。回归分析显示，每个患者的CTP-CBF值与PET-CBF值呈显著正相关(r=0.001.52~0.85，P<0.0 5)。结论：32 0排CT全脑CTP可用于评估慢性脑血管病患者全脑的缺血程度。
Objective: The 320-detector row computed tomography (CT) can provide whole-brain CT perfusion (CTP) maps with continuous angiographic images by performing a single dynamic scan. We investigated the reliability of CTP cerebral blood flow (CTP-CBF) with 320-detector row CT by comparing findings with O-15-positron emission tomography (PET-CBF).Methods: Whole-brain CTP and PET were performed in 10 patients with chronic unilateral steno-occlusive disease. We compared absolute and relative CBF values of bilateral middle cerebral artery territories between CTP and PET.Results: Although mean CTP-CBF values were approximately 30% lower than mean PET-CBF values, the mean ischemic-to-nonischemic CBF ratios of CTP and PET were almost identical (P = 0.804). Regression analysis showed a significant correlation between CTP-CBF and PET-CBF values for each patient (r = 0.52-0.85, P G 0.001).Conclusions: Whole-brain CTP using 320-detector row CT is useful for evaluating the degree of ischemia for the entire brain with chronic cerebrovascular disease.