Optimal waist-to-height ratio cutoff values for predicting cardio-metabolic risk in Han and Uygur adults in northwest part of China
Optimal waist-to-height ratio cutoff values for predicting cardio-metabolic risk in Han and Uygur adults in northwest part of China
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DOI：
10.1038/ejcn.2015.25
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发表时间：
2015-08-01
影响因子：
4.7
通讯作者：
Liu, F.
中科院分区：
文献类型：
--
作者：
He, C-H;Pan, S.;Liu, F.
背景/提示：在亚洲，预测心脏代谢风险的最佳肥胖指数研究较少。我们评估了最佳的腰高比（WHtR）预测高血压，血脂异常和糖尿病在新疆，中国西北部的一部分，汉族和维吾尔族人群。测量人体测量数据、血压、血清总胆固醇（TC）、甘油三酯、低密度脂蛋白、高密度脂蛋白和空腹血糖。结果：汉族和维吾尔族人群的WHtR与血压、总胆固醇、甘油三酯和空腹血糖均呈正相关（P均= 2），汉族男女均为0.54，维吾尔族男性为0.55，女性为0.57。WHtR高于或低于临界值的亚组之间的血压，甘油三酯和空腹血糖的一个显着差异，观察在两个种族.CONCLUSIONS：WHtR的最佳临界值是一个有用的筛选工具，预测在新疆，中国西北部的汉族和维吾尔族人群的心脏代谢风险。
BACKGROUND/OBJECTIVES: Optimal obesity indices in predicting cardio-metabolic risk are less studied in Asian. We evaluated optimal waist-to-height ratio (WHtR) for predicting hypertension, dyslipidemia and diabetes in Han and Uygur populations in Xinjiang, a northwest part of China.SUBJECTS/METHODS: This study involved 5603 Han and 4657 Uyghur participants. Anthropometric data, blood pressure, serum total cholesterol (TC), triglyceride, low-density lipoprotein, high-density lipoprotein and fasting glucose were determined. The cutoff values of WHtR were calculated; the relation between WHtR and prevalence of cardio-metabolic risks was evaluated.RESULTS: There was a positive correlation between WHtR and blood pressure, TC, triglycerides and fasting glucose in both Han and Uygur participants (all P= 2 of these risk factors were 0.54 for both men and women in Han and 0.55 in male and 0.57 in female Uygur participants. A significant difference in blood pressure, triglycerides and fasting glucose between subgroups with WHtR either above or below the cutoff values was observed in both men and women of the two ethnicities.CONCLUSIONS: The optimal cutoff value of WHtR is a useful screen tool for predicting cardio-metabolic risks in Han and Uygur population in Xinjiang, northwest part of China.