Prevalence of a metabolic syndrome phenotype in adolescents - Findings from the Third National Health and Nutrition Examination Survey, 1988-1994
Prevalence of a metabolic syndrome phenotype in adolescents - Findings from the Third National Health and Nutrition Examination Survey, 1988-1994
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DOI：
10.1001/archpedi.157.8.821
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发表时间：
2003-08-01
影响因子：
--
通讯作者：
Dietz, WH
中科院分区：
文献类型：
--
作者：
Cook, S;Weitzman, M;Dietz, WH
背景：在成年人中，代谢综合征是2型糖尿病和早发冠心病的重要危险因素。即便如此，目前还没有全国性的估计这种综合征在青少年中的患病率。目的：估计代谢综合征在美国青少年中的患病率和分布。设计和设置：第三次全国健康与营养调查横断面资料分析（1988-1994），这是管理的非制度化的美国平民人口的代表性样本。（n = 2430），主要结果测量：使用国家胆固醇教育计划，美国青少年中代谢综合征的患病率和分布结果：12 ~ 19岁青少年代谢综合征的总患病率为4.2%; 6.1%的男性和2.1%的女性受到影响（P =.01）。28.7%的超重青少年（体重指数[BMI]，大于或等于第95百分位数）存在该综合征，而6.8%的高危青少年（BMI，第85至第95百分位数）存在该综合征。
Background: In adults the metabolic syndrome imposes a substantial risk for type 2 diabetes mellitus and premature coronary heart disease. Even so, no national estimate is currently available of the prevalence of this syndrome in adolescents.Objective: To estimate the prevalence and distribution of a metabolic syndrome among adolescents in the United States.Design and Setting: Analyses of cross-sectional data obtained from the Third National Health and Nutrition Examination Survey (1988-1994), which was administered to a representative sample of the noninstitutionalized civilian population of the United States.Participants: Male and female respondents aged 12 to 19 years (n = 2430),Main Outcome Measures: The prevalence and distribution of a metabolic syndrome among US adolescents, using the National Cholesterol Education Pro-gram (Adult Treatment Panel III) definition modified for age.Results: The overall prevalence of the metabolic syndrome among adolescents aged 12 to 19 years was 4.2%; 6.1% of males and 2.1% of females were affected (P =.01). The syndrome was present in 28.7% of overweight adolescents (body mass index [BMI], greater than or equal to95th percentile) compared with 6.8% of at-risk adolescents (BMI, 85th to