TRABECULAR SPACING IN POSTMENOPAUSAL AUSTRALIAN WOMEN WITH AND WITHOUT VERTEBRAL FRACTURES
TRABECULAR SPACING IN POSTMENOPAUSAL AUSTRALIAN WOMEN WITH AND WITHOUT VERTEBRAL FRACTURES
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DOI：
10.1111/j.1445-5994.1992.tb02124.x
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发表时间：
1992-06-01
期刊：
影响因子：
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通讯作者：
VERNONROBERTS, B
中科院分区：
文献类型：
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作者：
MOORE, RJ;DURBRIDGE, TC;VERNONROBERTS, B
对32例椎体骨折妇女和37例无骨折妇女的髂嵴活检进行组织形态学测量。所有患者均为绝经后澳大利亚女性，因背痛到医院门诊内分泌科就诊。骨折病例的骨特征是单个骨小梁元素的丢失，剩余的骨小梁比非骨折妇女的骨小梁间隔更远（p < 0.0001）。这导致骨小梁体积显著减少（p < 0.01）。此外，类骨质表面减少（P < 0.01）。骨转换的动态参数在两组之间没有显著差异。这些数据应该是有用的评估髂骨骨组织形态计量学在澳大利亚绝经后妇女怀疑有骨质疏松症。
Histomorphometric measurements were made from iliac crest biopsies of 32 women with vertebral fractures and 37 women without fracture. All were post-menopausal Australian women who had presented with back pain to a hospital out-patient endocrinology clinic. Bone from the fracture cases was characterised by loss of individual trabecular elements, with the remaining trabeculae being spaced further apart than those in the non-fracture women (p < 0.0001). This resulted in a significant decrease in trabecular bone volume (p < 0.01). In addition osteoid surface was reduced (p < 0.01). Dynamic parameters of bone turnover were not significantly different between the two groups. These data should be useful for the assessment of iliac bone histomorphometry in Australian post-menopausal women suspected of having osteporosis.