Incidence and treatment of retinopathy of prematurity in England between 1990 and 2011: database study
Incidence and treatment of retinopathy of prematurity in England between 1990 and 2011: database study
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DOI：
10.1136/bjophthalmol-2014-305561
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发表时间：
2015-06-01
影响因子：
4.1
通讯作者：
Patel, C. K.
中科院分区：
文献类型：
--
作者：
Painter, Sally L.;Wilkinson, Andrew R.;Patel, C. K.
目的研究1990- 2011年英国早产儿视网膜病变（ROP）的发病率和治疗情况。方法分析英国国家医院发病统计数据，包括在医院出生的婴儿和住院婴儿，以获得ROP婴儿的年诊断率和治疗率。低出生体重（LBW）婴儿，出生时< 1500 g，因此有资格进行ROP筛查的国家数据，被用来作为计算ROP率每1000名婴儿在risk.Results记录的ROP发病率增加了10倍，从12.8每1000 LBW婴儿在1990年至125.5每1000 LBW婴儿在2011年。在1990年至2011年期间，通过冷冻疗法或激光治疗ROP的比率从每1000名LBW婴儿1.7上升到14.8。1990年，13.3%的ROP婴儿接受冷冻治疗，2011年下降到0.1%。激光治疗率从1999年的1.8%上升到2011年的11.7%。结论新生儿存活率的提高、对ROP认识的提高以及ROP筛查和治疗指导的普及都将有助于1990 - 2011年ROP发病率的大幅上升。视网膜消融术现在几乎总是使用激光治疗而不是冷冻治疗。
Aims To study the incidence and treatment of retinopathy of prematurity (ROP) in England, 1990-2011.Methods English national Hospital Episode Statistics were analysed, for babies born in hospital and for inpatient admissions, to obtain annual rates of diagnosis of, and treatment for, babies with ROP. National data on low birthweight (LBW) babies, born < 1500 g and therefore eligible for ROP screening, were used as denominators in calculating rates of ROP per 1000 babies at risk.Results The recorded incidence of ROP increased tenfold, from 12.8 per 1000 LBW babies in 1990 to 125.5 per 1000 LBW babies in 2011. Tretment rates for ROP by cryotherapy or laser rose from 1.7 to 14.8 per 1000 LBW babies between 1990 and 2011. In 1990, 13.3% of babies with ROP were treated with cryotherapy, which fell to 0.1% in 2011. Rates for laser treatment rose from 1.8% of babies with ROP in 1999 to 11.7% in 2011.Conclusions Increased neonatal survival, improved awareness of ROP and dissemination of guidance on screening and treatment of ROP will all have contributed to the substantial rise in recorded incidence of ROP between 1990 and 2011. Retinal ablation is now almost always performed using laser treatment rather than cryotherapy.