Comparison of sensitivity and reading time for the use of computer-aided detection (CAD) of pulmonary nodules at MDCT as concurrent or second reader
Comparison of sensitivity and reading time for the use of computer-aided detection (CAD) of pulmonary nodules at MDCT as concurrent or second reader
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DOI：
10.1007/s00330-007-0667-1
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发表时间：
2007-11-01
影响因子：
5.9
通讯作者：
Wormanns, D.
中科院分区：
文献类型：
--
作者：
Beyer, F.;Zierott, L.;Wormanns, D.
本研究的目的是比较使用CAD作为第二阅读器（SR）和同时阅读器（CR）时，MDCT扫描对肺结节的检测灵敏度和放射科医生的阅读时间。四名放射科医生分析了从临床常规中选择的50次胸部MDCT扫描，并将所有检测到的肺结节标记为：第一次将CAD标记为CR（在阅读过程中立即显示CAD结果），随后（中位14周）将CAD标记为SR（完成首次阅读后显示CAD标记，无CAD）。使用了西门子luncad原型机。记录检测结节的灵敏度和读数时间。以CAD为SR的读数灵敏度显著高于不以CAD为SR的读数（p < 0.001）和以CAD为CR的读数（p < 0.001）。对于1.75 mm及以上的结节，CAD作为CR与非CAD的读数在敏感性上无显著差异；例如，对于大于4 mm的结节，无CAD的敏感性为68%，CAD作为CR的敏感性为68% (p=0.45)， CAD作为SR的敏感性为75% （p < 0.001）。与无CAD （294 s, p=0.04）和SR （337 s, p < 0.001）相比，CR组的阅读时间显著缩短（274 s）。在我们的研究中，CAD作为CR可以加快胸部CT病例对肺结节的读取速度而不降低灵敏度，而作为SR则可以以延长读取时间为代价提高灵敏度。
The purpose of this study was to compare sensitivity for detection of pulmonary nodules in MDCT scans and reading time of radiologists when using CAD as the second reader (SR) respectively concurrent reader (CR). Four radiologists analyzed 50 chest MDCT scans chosen from clinical routine two times and marked all detected pulmonary nodules: first with CAD as CR (display of CAD results immediately in the reading session) and later (median 14 weeks) with CAD as SR (display of CAD markers after completion of first reading without CAD). A Siemens LungCAD prototype was used. Sensitivities for detection of nodules and reading times were recorded. Sensitivity of reading with CAD as SR was significantly higher than reading without CAD (p < 0.001) and CAD as CR (p < 0.001). For nodule size of 1.75 mm or above no significant sensitivity difference between CAD as CR and reading without CAD was observed; e.g., for nodules above 4 mm sensitivity was 68% without CAD, 68% with CAD as CR (p=0.45) and 75% with CAD as SR (p < 0.001). Reading time was significantly shorter for CR (274 s) compared to reading without CAD (294 s; p=0.04) and SR (337 s; p < 0.001). In our study CAD could either speed up reading of chest CT cases for pulmonary nodules without relevant loss of sensitivity when used as CR, or it increased sensitivity at the cost of longer reading times when used as SR.