Tracking of cardiovascular risk factors - The Tromso study, 1979-1995
Tracking of cardiovascular risk factors - The Tromso study, 1979-1995
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DOI：
10.1093/aje/154.5.418
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发表时间：
2001-09-01
影响因子：
5
通讯作者：
Arnesen, E
中科院分区：
文献类型：
--
作者：
Wilsgaard, T;Jacobsen, BK;Arnesen, E
在普通成年人中，对心血管危险因素(血压、体重指数(BMI)和血脂)的跟踪研究还不多。目前还没有一项已知的研究比较了两性对这些因素的跟踪。在本研究中，17,710名年龄在20-61岁的男性和女性参加了两到三个以人口为基础的研究。挪威特罗姆索历时16年(1979-1980年至1994-1995年)的健康调查。用不同的方法估计了跟踪系数，找到了可能的跟踪预测因子。BMI的跟踪程度很高(总体跟踪系数：男性为0.85，女性为0.80)。对收缩压(性别相关系数：0.52，0.54)、舒张压的跟踪相对较高(或中等)。(0.48，0.48)、高密度脂蛋白胆固醇(0.55，0.64)和总胆固醇(0.77，0.65)。相关系数最低的是甘油三酯(0.43，0.39)。对高六分位数的跟踪分析证实了这些结果。尽管一些基线预测因素与跟踪有关，但影响相对较弱。当评估追踪上六分位数的预测因子时，发现有显著关联。影响比较大。在追踪中没有观察到显著的性别差异。然而，女性比男性更有可能保持在收缩压和舒张压以及BMI的上六分位数。
Tracking of cardiovascular risk factors (blood pressure, body mass index (BMI), and serum lipids) has not been studied much in a general, adult population. No known study has compared tracking of these factors for both sexes. In the present study, 17,710 men and women aged 20-61 years at baseline attended two or three population-based. health surveys in Tromso, Norway, over 16 years (between 1979-1980 and 1994-1995). Tracking coefficients were estimated by using different methods, and possible predictors of tracking were found. There was a high degree of tracking for BMI (overall tracking coefficients: 0.85 for men, 0.80 for women). Relatively high (or moderate) tracking was found for systolic blood pressure (respective sex-specific coefficients: 0.52, 0.54), diastolic blood pressure. (0.48, 0.48), high density lipoprotein cholesterol (0.55, 0.64), and total cholesterol (0.77, 0.65). The lowest coefficients were for triglycerides (0.43, 0.39). Analysis of tracking in the upper sextile confirmed these results. Although some baseline predictors were associated with tracking, the effects were relatively weak. When predictors for tracking in the upper sextile were assessed, significant associations were found with. relatively strong effects. No major sex differences were observed in tracking. However, women were more likely than men to remain in the upper sextile of systolic and diastolic blood pressures and of BMI.