Application of a high-pressure electro-osmotic pump using nanometer silica in capillary liquid chromatography
Application of a high-pressure electro-osmotic pump using nanometer silica in capillary liquid chromatography
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DOI：
10.1016/j.chroma.2004.11.085
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发表时间：
2005-01-28
影响因子：
4.1
通讯作者：
Liu, KH
中科院分区：
文献类型：
--
作者：
Chen, LX;Guan, YF;Liu, KH
使用三个内径为 20 cm x 530 mum 的泵组装了一种结构简单的新颖设计的电渗泵（EOP）。填充有 20 +/- 5 nm 二氧化硅颗粒的熔融石英毛细管，用于毛细管液相色谱。结果发现，在施加电压小于10 kV的情况下，该泵可以为大多数输送的液体产生超过20 MPa的压力和几μL/min的流量。通过增加压力、降低施加电压和电流，热力学效率约为1-4%。 EOP 在 20 cm x 150 mum i.d. 中的实际应用3 mum C-18 熔融石英分析毛细管柱证明了该泵的适用性。 (C) 2004 Elsevier B.V. 保留所有权利。
A novel designed electro-osmotic pump (EOP) with simple structure was assembled using three 20 cm x 530 mum i.d. fused-silica capillaries packed with 20 +/- 5 nm silica grains for capillary liquid chromatography. It was found that the pump could generate pressures over 20 MPa and several muL/min flow rate for most of the liquids being delivered with the applied voltage less than 10 kV. By increasing the pressure, decreasing the applied voltage and the electrical current, the thermodynamic efficiency was about 1-4%. A practical application of the EOP in a 20 cm x 150 mum i.d. 3 mum C-18 fused-silica analytical capillary column demonstrated the applicability of the pump. (C) 2004 Elsevier B.V. All rights reserved.