Obesity, increased linear growth, and risk of type 1 diabetes in children
Obesity, increased linear growth, and risk of type 1 diabetes in children
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DOI：
10.2337/diacare.23.12.1755
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发表时间：
2000-12-01
期刊：
影响因子：
16.2
通讯作者：
Åkerblom, HK
中科院分区：
文献类型：
--
作者：
Hyppönen, E;Virtanen, SM;Åkerblom, HK
目的：本研究的目的是评估肥胖和线性增长对儿童患1型糖尿病风险的影响。研究与方法--研究人群由所有糖尿病儿童组成(120%)，3岁以后患1型糖尿病的风险增加一倍以上。结论-目前观察到肥胖和快速线性增长是儿童1型糖尿病的危险因素，这表明在过去几十年中，大多数工业化国家肥胖和长期增长的患病率的增加可能与许多国家同时观察到的1型糖尿病发病率的增加有关。
OBJECTIVE - The purpose of the present study was to evaluate the effect of obesity and linear growth on the risk of developing type 1 diabetes in children. RESEARCHDESIGN AND METHODS - The study population consists of all diabetic children 120%) after 3 years of age was associated with a more than twofold risk of developing type 1 diabetes.CONCLUSIONS - The present observation that obesity and rapid linear growth are risk factors for type 1 diabetes in children indicates that the increase in the prevalence of obesity and secular growth that has occurred in most industrialized countries over the last decades may be involved in the increase in type 1 diabetes incidence simultaneously observed in many countries.