Infection in the patient receiving chemotherapy for cancer: oral considerations.

Infection in the patient receiving chemotherapy for cancer: oral considerations.
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接受癌症化疗的患者的感染:口腔注意事项。

DOI:
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发表时间:
1984
期刊:
The Journal of the American Dental Association (1939)
影响因子:
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通讯作者:
T. McElroy
T. McElroy
中科院分区:
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文献类型:
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作者:
T. McElroy

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由于与疾病过程和治疗相关的多种因素,接受癌症化疗的患者极易受到感染,感染约占患者死亡的70%。当考虑接受癌症化疗的患者的潜在感染源时,口腔为微生物生长提供了理想的条件,特别是在虚弱的患者中,并且口腔是肺部、消化道和循环系统污染的入口。由于口腔菌群的致病性增强和宿主防御机制受损,这些患者更容易受到口腔感染。接受癌症化疗的患者的口腔/牙科管理将增强患者的整体健康和舒适度,并预防或减少口腔并发症,包括粘膜炎以及局部和全身感染。
Because of the various factors associated with the disease process and its treatment, the patient receiving chemotherapy for cancer is highly susceptible to infection, and infection accounts for approximately 70% of patient fatalities. When potential sources of infection are considered in the patient receiving chemotherapy for cancer, the mouth provides ideal conditions for microbial growth, particularly in the debilitated patient, and is a portal of entry for contamination of the lungs, the digestive tract, and the circulatory system. These patients are more susceptible to oral infection because of alteration of oral flora toward greater pathogenicity and impairment of host-defense mechanisms. Oral/dental management of the patient receiving chemotherapy for cancer will enhance the general health and comfort of the patient and will prevent or reduce oral complications including mucositis and local and systemic infection.