Cortisol levels and conduct disorder in adolescent mothers
Cortisol levels and conduct disorder in adolescent mothers
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DOI：
10.1097/00004583-200404000-00012
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发表时间：
2004-04-01
影响因子：
13.3
通讯作者：
Tremblay, RE
中科院分区：
文献类型：
--
作者：
Azar, R;Zoccolillo, M;Tremblay, RE
目的：探讨皮质醇水平与青少年母亲品行障碍（CD）的关系。过去的研究表明，低水平的皮质醇与CD有关，特别是与其侵略性症状有关。作者检验了这一假设，即患有CD的青少年母亲在产后4个月和9个月时的唾液皮质醇水平低于没有CD的母亲。方法：在产后4个月和9个月的实验室访视期间，测量了228名青少年母亲（分娩年龄16.9 ± 1岁[平均值± SD]）的上午唾液皮质醇水平。根据反社会人格障碍（DSM-III-R）标准的CD小节，在妊娠期间诊断CD。结果：结果没有证实假设。较低的皮质醇水平与CD诊断、CD症状数量或侵袭性症状无显著相关性。结论：尽管有效的措施和强大的统计力量，这项研究未能发现皮质醇水平和CD之间的联系，在青少年母亲的样本。结果可能受到以下事实的影响：参与者产后4个月和9个月，以及将患有CD的母亲与生活在压力环境中的母亲进行比较。
Objective: To examine the association between cortisol levels and conduct disorder (CD) in adolescent mothers. Past research has shown that low levels of cortisol were associated with CD, particularly with its aggressive symptoms. The authors tested the hypothesis that adolescent mothers with CD would show lower levels of salivary cortisol compared to mothers without CD at 4 and 9 months postpartum. Method: Midmorning salivary cortisol levels were measured in 228 adolescent mothers (age at delivery 16.9 +/- 1 years [mean +/- SD]) during a laboratory visit at 4 and 9 months postpartum. CD was diagnosed during pregnancy according to the CD subsection on the criteria for antisocial personality disorder (DSM-III-R). Results: Results did not confirm the hypothesis. Lower cortisol levels were not significantly associated with a CD diagnosis, the number of CD symptoms, or aggressive symptoms. Conclusions: Despite valid measures and strong statistical power, this study failed to find an association between cortisol levels and CD in a sample of adolescent mothers. The results may have been influenced by the fact that participants were 4 and 9 months postpartum and by comparisons of mothers with CD to mothers living in stressful circumstances.