Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-lalpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.

Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-lalpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.
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与缺氧诱导因子-lα氧依赖性降解结构域融合的减毒白喉毒素A的缺氧调节表达优先诱导实体瘤中缺氧细胞的凋亡。

DOI:
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发表时间:
2005
期刊:
Cancer Ressearch 65・24
影响因子:
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通讯作者:
Takenaga K.
Takenaga K.
中科院分区:
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文献类型:
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作者:
Koshikawa N;Takenaga K.

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