Number and size of uterine fibroids and obstetric outcomes
Number and size of uterine fibroids and obstetric outcomes
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DOI：
10.3109/14767058.2014.921675
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发表时间：
2015-03-01
影响因子：
1.8
通讯作者：
Tranquilli, Andrea Luigi
中科院分区：
文献类型：
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作者：
Ciavattini, Andrea;Clemente, Nicolo;Tranquilli, Andrea Luigi
目的：估计超声检查发现的多发性或大（直径>= 5厘米）子宫肌瘤对产科结局的影响。方法：对219名患有子宫肌瘤的女性（在3年内的常规妊娠中期超声调查中发现）进行回顾性队列研究，2010-2012年）及其年龄匹配的对照组。纳入标准为单胎妊娠、妊娠24周以上分娩、无病理状况（慢性高血压、妊娠期糖尿病或既往存在的糖尿病、子宫畸形或胎儿畸形）。结果：与无肌瘤的妇女相比，多发性肌瘤妇女（n = 34）的早产率显著增高（29.4%对5%，P < 0.05）。
Objective: Estimating the impact of sonographically identified multiple or large (>= 5 cm in diameter) fibroids on obstetric outcomes.Methods: Retrospective cohort study of 219 women with uterine fibroids (identified on a routine second-trimester ultrasound survey over a 3-year period, 2010-2012) and their age-matched controls. Inclusion criteria were singleton pregnancy, delivery at >24 weeks of gestation and no pathological conditions (chronic hypertension, gestational diabetes or pre-existing diabetes mellitus, uterine anomalies or fetal malformations).Results: Compared to women with no fibroids, women with multiple fibroids (n = 34) had a significantly higher rate of preterm birth (29.4% versus 5%, p