Innate immunity: Lipoproteins take their Toll on the host

Innate immunity: Lipoproteins take their Toll on the host
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DOI:
10.1016/s0960-9822(00)80073-1
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发表时间:
1999-12-02
期刊:
影响因子:
9.2
通讯作者:
Medzhitov, R
Medzhitov, R
中科院分区:
生物学1区
文献类型:
--
作者:
Janeway, CA;Medzhitov, R

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哺乳动物Toll样受体(TLR)家族在微生物感染的识别中具有关键作用。最近的证据表明,细菌脂蛋白是细菌细胞壁的主要成分,被人类TLR家族的成员识别。
A family of mammalian Toll-like receptors (TLRs) has a critical role in the recognition of microbial infection. Recent evidence suggests that bacterial lipoproteins major components of bacterial cell walls - are recognized by a member of the human TLR family.