Distribution of ultrasonographically-assessed dimensions of common carotid arteries in healthy adults of both sexes
Distribution of ultrasonographically-assessed dimensions of common carotid arteries in healthy adults of both sexes
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DOI：
10.1016/s0021-9150(99)00276-2
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发表时间：
2000-02-01
期刊：
影响因子：
5.3
通讯作者：
Simon, A
中科院分区：
文献类型：
--
作者：
Denarié, N;Gariepy, J;Simon, A
我们的目标是提供“正常”颈动脉尺寸的描述，该尺寸越来越多地用于检测早期动脉粥样硬化和预测临床并发症。使用自动计算机边缘检测程序，通过 B 型超声在两侧颈总动脉远端 1 cm 段上测量远壁内膜中层厚度 (IMT)、管腔直径和横截面积内膜中层厚度 (CSA-IMT)。研究对象为 133 名男性和 216 名女性，年龄在 17-65 岁之间，没有心血管疾病和传统危险因素。无论性别还是两侧，IMT 和 CSA-IMT 都会随着年龄的增长而增加，而直径则不会（男性右侧除外）。 30 岁或以下时，女性的直径比男性小，但左侧除外。虽然 IMT 在性别之间没有差异，但 31 至 50 岁的左侧除外，其中男性的 IMT 较高，但由于直径较小，女性的 CSA-IMT 低于男性，但 50 岁以上的右侧除外。除 30 岁及以下男性和 31 至 40 岁女性外，两种性别的 IMT 右侧均低于左侧，而 31-40 岁男性和女性以及 41-50 岁女性的右侧直径高于左侧；此外，40 岁以上的男性和女性的 CSA-IMT 右侧均低于左侧。这些数据提供了颈动脉尺寸的参考值，并表明在临床实践和试验中解释 IMT 和直径的“正常”值时应考虑年龄、性别和测量侧。 (C) 2000 Elsevier Science Ireland Ltd. 保留所有权利。
Our objective was to provide a description of 'normal' carotid artery dimensions which are increasingly used for detecting early atherosclerosis and predicting clinical complications. Far wall intima-media thickness (IMT), lumen diameter and cross-sectional area intima-media thickness (CSA-IMT) were measured on 1 cm-distal common carotid artery segments on both sides by B-mode ultrasound, using an automated computerized edge-detection program. in 133 men and 216 women aged 17-65 years and free from cardiovascular disease and traditional risk factors. IMT and CSA-IMT increased with age in both sexes and on both sides, while diameter did not, except on the right side in men. Women had lower diameter than men except on the left side at 30 years or below. while IMT did not differ between sexes except on the left side from 31 to 50 years where IMT was higher in men, as a result of their lower diameter, women had lower CSA-IMT than men except on the right side above 50 years. IMT was lower on the right side than on the left side in both sexes, except in 30-year old or younger men and 31- to 40-year old women, while diameter was higher on the right side than on the left side in men and women aged 31-40 years and in women aged 41-50 years; also CSA-IMT was lower on the right side than on the left side in both sexes above 40 years. These data provide reference values of carotid artery dimensions and show that age, sex and side of measurement should be taken into account in the interpretation of 'normal' values of IMT and diameter in clinical practice and trials. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.