Velcrands with snaps and their conformational control
Velcrands with snaps and their conformational control
复制标题
带按扣的 Velcrands 及其构象控制
作者：
Tucci;Rudkevich;Rebek
制备了一类通过分子间作用力实现二聚化的新型自折叠聚合物。扩展π表面上的疏溶剂相互作用稳定了二聚体，类似于维兰德，而8个氢键像扣扣一样将分子固定在一起。在间苯二甲酸乙酯基空腔体的上边缘上加入了自互补的氢键位点阵列。通过溶剂极性的变化，内部腔体的形状和大小发生了戏剧性的重组。具体来说，在芳香溶剂（或CDCl3）和[D6]DMSO的混合物中，扩展表面（D2d对称）和深腔（C4v对称）之间的平衡可以被操纵。构象的转换和二聚化基序非常适合于非共价聚合物材料的组装。
A novel class of self-folding velcrands was prepared that dimerize through intermolecular forces. Solvophobic interactions on extended pi surfaces stabilize the dimer similar to velcrands, while eight hydrogen bonds act like snaps to hold the molecules together. The self-complementary array of hydrogen bonding sites were incorporated on the upper rim of a resorcinarene-based cavitand. A dramatic reorganization of shape and size of the internal cavity was manifested through changes in solvent polarity. Specifically, the equilibrium between the extended surface (D2d symmetry) and a deep cavity (C4v symmetry) could be manipulated in mixtures of aromatic solvents (or CDCl3) and [D6]DMSO. The switching of conformations and the dimerization motif are well-suited for the assembly of noncovalent polymeric materials.