Electroencephalogram Discharges in Atypical Cognitive Development
Electroencephalogram Discharges in Atypical Cognitive Development
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DOI：
10.1177/0883073809344743
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发表时间：
2010-05-01
影响因子：
1.9
通讯作者：
Papanicolaou, Andrew
中科院分区：
文献类型：
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作者：
Frye, Richard E.;Butler, Ian;Papanicolaou, Andrew
为了探讨脑电(EEG)放电的意义及其治疗，我们回顾了22例认知发育不典型的儿童的病历，这些儿童对标准的教育治疗没有反应，并在EEG上表现为放电。大多数儿童没有明显的癫痫症状，发育倒退和/或波动很少见。大多数儿童表现出语言和注意力障碍以及自闭症症状，并在脑电图上有多灶性放电。在接受抗癫痫药物治疗的20例患者中，70%的患者在1次门诊中有明显改善。这项研究表明，患有EEG放电和发育认知障碍的儿童在EEG上表现出独特的症状和放电模式。这项研究表明，对标准治疗无效的发育认知障碍儿童，如果检测到放电，可能会从脑电筛查和抗癫痫调节试验中受益。
To investigate the significance of electroencephalogram (EEG) discharges and their treatment, we retrospectively reviewed the charts of 22 children with atypical cognitive development that did not respond to standard educational therapy and demonstrated discharges on EEG. Most children demonstrated no obvious symptoms of seizures, and developmental regression and/or fluctuations were uncommon. The majority of children demonstrated a language and attention disorder and autism symptomatology and had multifocal discharges on EEGs. Of the 20 patients treated with antiepileptic medications, 70% demonstrated definite improvement within 1 clinic visit. This study suggests that children with EEG discharges and developmental cognitive disorders demonstrate a unique pattern of symptomatology and discharges on EEG. This study suggests that children with developmental cognitive disorders that do not respond to standard therapy may benefit from screening with an EEG and a trial of antiepileptic mediation if discharges are detected.