The Amsterdam Pain Management Index compared to eight frequently used outcome measures to evaluate the adequacy of pain treatment in cancer patients with chronic pain
The Amsterdam Pain Management Index compared to eight frequently used outcome measures to evaluate the adequacy of pain treatment in cancer patients with chronic pain
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DOI：
10.1016/s0304-3959(00)00455-3
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发表时间：
2001-04-01
期刊：
影响因子：
7.4
通讯作者：
Abu-Saad, HH
中科院分区：
文献类型：
--
作者：
de Wit, R;van Dam, F;Abu-Saad, HH
没有“金标准”来评估癌症患者疼痛治疗的充分性。本研究的目的是探讨阿姆斯特丹疼痛管理指数，一个新设计的衡量癌症疼痛治疗的充分性，并将其与八个常用的结果指标进行比较。阿姆斯特丹疼痛管理指数比较患者的当前疼痛强度，平均疼痛强度。和最差疼痛强度与所用止痛药的综合评分，同时校正患者认为可耐受的疼痛水平。八个常用的结果测量包括三个疼痛强度标记，疼痛缓解量表，患者满意度量表，和三个疼痛管理指数在一项随机对照试验中，313例癌症患者的疼痛持续时间至少1个月，并随访三次，直到出院后2个月在家里。实验组接受疼痛教育计划，包括量身定制的疼痛信息和指导。结果显示，除三项疼痛管理指标外，这些措施之间的一致性很低，中等。已知组间比较和组间等效性的检验表明，阿姆斯特丹疼痛管理指数显示出有希望的结果。疼痛强度标记物和疼痛缓解量表在区分组间差异有限，而患者满意度量表显示患者组间无差异。虽然疼痛管理指数可以区分患者组，但差异不在预期方向。所有结局指标均清楚地证明了结局指标检测随时间变化的能力。干预的效果仅见于阿姆斯特丹疼痛管理指数和患者的实质性最严重疼痛评分。虽然支持使用阿姆斯特丹疼痛管理指数，但需要更多的研究。(C)2001年国际疼痛研究协会。由Elsevier Science B.V.出版，版权所有。
There is no 'gold standard to assess the adequacy of pain treatment in cancer patients. The purpose of the study is to explore the Amsterdam Pain Management Index, a newly designed measure to evaluate the adequacy of cancer pain treatment, and to compare it with eight frequently used outcome measures. The Amsterdam Pain Management Index compares patients Present Pain Intensity, Average Pain Intensity. and Worst Pain Intensity with a composite score of analgesics used, while correcting for what a patient considers as a tolerable level of pain. The eight frequently used outcome measure consisted of three Pain Intensity Markers, the Pain Relief Scale, the Patient Satisfaction Scale, and three Pain Management Indexes In a randomized controlled trial, 313 cancer patients with a pain duration of at least 1 month were included and followed-up three times until 2 months postdischarge at home. The experimental group received a Pain Education Program, consisting of tailored pain information and instruction. Results showed that, except for the three Pain Management Indexes. the agreement between the measures was very low to moderate. The test of known-groups comparisons and equivalence between groups indicated that the Amsterdam Pain Management Index showed promising results. The Pain Intensity Markers and the Pain Relief Scale were limited in discriminating between groups, while the Patient Satisfaction Scale showed no differences between patient groups. Although it was possible for the Pain Management Indexes to distinguish between patient groups, the differences were not in the expected direction. The ability of the outcome measures to detect changes over time was clearly demonstrated by all outcome measures. Effects of the intervention were only found for the Amsterdam Pain Management Index and patients' Substantial Worst Pain score. Although support was provided for the use of the Amsterdam Pain Management Index, more research is warranted. (C) 2001 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved.