Severe Malarial Thrombocytopenia: A Risk Factor for Mortality in Papua, Indonesia
Severe Malarial Thrombocytopenia: A Risk Factor for Mortality in Papua, Indonesia
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DOI：
10.1093/infdis/jiu487
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发表时间：
2015-02-15
影响因子：
6.4
通讯作者：
Price, Ric N.
中科院分区：
文献类型：
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作者：
Lampah, Daniel A.;Yeo, Tsin W.;Price, Ric N.
背景血小板减少症对疟疾发病率和死亡率的重要性尚不清楚。我们比较了在南巴布亚巴布亚的疟疾患者和非疟疾患者的血小板计数和临床相关性。对2004年4月至2012年12月期间到转诊医院就诊的患者的数据进行整理。215479例患者（23.4%）进行了血小板测量，其中66421例（30.8%）患有临床疟疾。恶性疟原虫单一感染的患者血小板计数最低，严重血小板减少症的风险最大（血小板计数，
Background. The significance of thrombocytopenia to the morbidity and mortality of malaria is poorly defined. We compared the platelet counts and clinical correlates of patients with and those without malaria in southern Papua, Indonesia.Methods. Data were collated on patients presenting to a referral hospital between April 2004 and December 2012.Results. Platelet measurements were available in 215 479 patients (23.4%), 66 421 (30.8%) of whom had clinical malaria. Patients with Plasmodium falciparum monoinfection had the lowest platelet counts and greatest risk of severe thrombocytopenia (platelet count,