What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer
What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer
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什么痣是发育异常、一种综合征，也是恶性黑色素瘤最常见的先兆？
作者：
A. Ackerman
本文批判性地探讨了“发育不良”的概念，因为它适用于黑素细胞瘤，并得出结论，这一概念是有缺陷的。对发育不良性痣和发育不良性痣综合征概念的有效性也有疑问。作者认为，大多数恶性黑色素瘤是新发的，而不是在既存的发育不良痣中发生的。由于作者认为所谓的发育不良痣是人类最常见的黑色素细胞痣，并且没有核色素沉着，因此他建议将其重新命名为“普通痣”，以便于患者的同情，准确性和护理。最后，有人建议，解决黑素细胞瘤领域的问题可能会更容易完成的术语，如发育不良，发育不良细胞，发育不良痣，和发育不良痣综合征避开。
This essay examines critically the concept of ‘dysplasia’ as it applies to melanocytic neoplasia and concludes that the concept is flawed. Doubt is cast also upon the validity of the concepts of a dysplastic naevus and a dysplastic naevus syndrome. The author is of the view that most malignant melanomas arise de novo and not in pre‐existing dysplastic naevi. Because so‐called dysplastic naevi are considered by the author to be the commonest melanocytic naevi in man and devoid of nuclear atypia, he proposes that they be re‐named ‘common naevi’ in the interest of symplicity, accuracy, and care of patients. Lastly, it is suggested that resolution of problems in the sphere of melanocytic neoplasia might be accomplished more readily were terms like dysplasia, dysplastic cells, dysplastic naevi, and the dysplastic naevus syndrome eschewed.
影响因子：
3.3
作者：
CLARK, WH;ELDER, DE;VANHORN, M
通讯作者：
VANHORN, M
关于发育不良痣和恶性黑色素瘤的想法交流。
DOI：
--
发表时间：
1985
期刊：
The American Journal of dermatopathology
影响因子：
--
作者：
Ackerman,AB;Elder,DE
通讯作者：
Elder,DE