Two-dimensional thick-slice MR digital subtraction anglography in the assessment of small to medium-size intracranial arteriovenous malformations
Two-dimensional thick-slice MR digital subtraction anglography in the assessment of small to medium-size intracranial arteriovenous malformations
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DOI：
10.1007/s00234-002-0844-5
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发表时间：
2003-01-01
期刊：
影响因子：
2.8
通讯作者：
Ohtomo, K
中科院分区：
文献类型：
--
作者：
Mori, H;Aoki, S;Ohtomo, K
通过传统导管血管造影评估颅内动静脉畸形（AVM）存在风险；此外，这种侵入性手术经常会重复进行以进行随访。我们研究了具有高时间分辨率的二维厚层对比增强磁共振数字减影血管造影 (2D MRDSA) 在 AVM 评估中的临床适用性。我们在 1.5 特斯拉成像仪上对经过处理或未经处理的中小型 AVM 进行了 78 项 2D MRDSA 研究。两名观察者使用三点分级标准独立评估了 T2 加权图像上的病灶流空洞演示以及 2D MRDSA 上 AVM 的每个组成部分。在 55 例 AVM 患者中，MRI 上血管巢流空、供血血管、血管巢、引流血管和早期静脉充盈的平均评分分别为 2.8、2.4、2.6、2.8 和 2.8。使用 2D MRDSA 的 AVM 的敏感性、特异性、阳性和阴性预测值分别为 87、100、100 和 78%，而 T2 加权图像上的病灶流空洞的敏感性、特异性、阳性和阴性预测值分别为 80、91、96 和 66%。因此，2D MRDSA 可以展示 AVM 的血流动力学特征。它可以用作侵入性较小的动态血管造影工具，用于对先前通过导管血管造影描绘的 AVM 进行随访。
Assessment of intracranial arteriovenous malformations (AVMs) by conventional catheter angiography carries risks; moreover, this invasive procedure is often repeated for follow-up. We investigated the clinical applicability of two-dimensional thick-slice, contrast-enhanced magnetic resonance digital subtraction angiography (2D MRDSA) with high temporal resolution in the assessment of AVMs. We performed 78 2D MRDSA studies of treated or untreated small to medium-size AVMs on a 1.5 tesla imager. Two observers independently evaluated demonstration of nidus flow void on T2-weighted images and each component of the AVM on 2D MRDSA employing a three-point grading scale. In 55 patients with AVMs, the mean ratings of nidus flow voids, feeding vessels, nidi, draining vessels and early venous filling on MRI were 2.8, 2.4, 2.6, 2.8 and 2.8, respectively. sensitivity, specificity, positive and negative predictive values for an AVM using 2D MRDSA were 87, 100, 100 and 78%, respectively and for nidus flow voids on T2-weighted images 80, 91, 96 and 66%, respectively. 2D MRDSA can thus demonstrate haemodynamic features of AVMs. It can be employed as a less invasive, dynamic angiographic tool for follow-up of AVMs previously delineated by catheter angiography.