SPACE: a suite of tools for protein structure prediction and analysis based on complementarity and environment.
SPACE: a suite of tools for protein structure prediction and analysis based on complementarity and environment.
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DOI：
10.1093/nar/gki398
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发表时间：
2005-07-01
影响因子：
14.9
通讯作者：
Edelman M
中科院分区：
文献类型：
--
作者：
Sobolev V;Eyal E;Gerzon S;Potapov V;Babor M;Prilusky J;Edelman M
我们描述了一套分析和预测生物分子及其复合物结构的SPACE工具。LPC/CSU软件提供了原子间接触和接触表面互补性的通用定义，以分析蛋白质结构和复合物。在LPC/CSU的当前版本中，增加了水分子和核酸的分析，以及使用Chime或基于Java的Jmol改进和扩展的可视化选项。SPACE套件包括服务器和程序：点突变的结构分析（MutaProt）;基于表面互补性的侧链建模（SCCOMP）;构建晶体环境和分析晶体接触（CryCo）;蛋白质接触图（CMA）的构建和分析以及分子对接软件（LIGIN）。SPACE套房的访问地址为。
We describe a suite of SPACE tools for analysis and prediction of structures of biomolecules and their complexes. LPC/CSU software provides a common definition of inter-atomic contacts and complementarity of contacting surfaces to analyze protein structure and complexes. In the current version of LPC/CSU, analyses of water molecules and nucleic acids have been added, together with improved and expanded visualization options using Chime or Java based Jmol. The SPACE suite includes servers and programs for: structural analysis of point mutations (MutaProt); side chain modeling based on surface complementarity (SCCOMP); building a crystal environment and analysis of crystal contacts (CryCo); construction and analysis of protein contact maps (CMA) and molecular docking software (LIGIN). The SPACE suite is accessed at .