Prevalence and prognosis of electrocardiographic findings in middle-aged men.

Prevalence and prognosis of electrocardiographic findings in middle-aged men.
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中年男性心电图检查结果的患病率和预后。

DOI:
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发表时间:
1978
影响因子:
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通讯作者:
P. McCartney
P. McCartney
中科院分区:
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文献类型:
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作者:
G. Rose;P. Baxter;D. Reid;P. McCartney

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对18403名年龄在40至64岁之间的男性公务员进行了筛选检查,包括明尼苏达州代码编码的心电图(仅肢体导联),采用严格的质量控制。研究结果与冠状动脉心脏病的相关性已根据随后五年的年龄趋势、症状史和冠状动脉心脏病死亡率进行了测试。Q波、电轴左偏、ST段压低和T波改变(包括作为孤立发现的微小T波项目)、心室传导缺陷和房颤的结果为阳性;但R振幅增加、PR间期延长或缩短、QT间期持续时间、早搏和心率极值的结果通常不令人印象深刻。筛选时发现的特定心电图结果的预后与临床实践中出现的结果完全不同。在这项研究中,有6%的男性出现了提示缺血的模式,随后的冠心病死亡率每年略高于1%;而在那些没有症状的人中,这一数字甚至更低。
A screening examination including an electrocardiogram (limb leads only) coded by the Minnesota Code, using rigorous quality control was done on 18 403 male civil servants aged 40 to 64. The association of the findings with coronary heart disease has been tested in relation to age trends, symptomatic history, and coronary heart disease mortality rates in the ensuing five years. The results were positive for Q waves, left axis deviation, ST depression, and T wave changes (including minor T wave items as an isolated finding), ventricular conduction defects, and atrial fibrillation; but they were generally unimpressive for increased R amplitude and for lengthening or shortening of the PR interval, QT interval duration, premature beats, and extremes of heart rate. The prognosis of specific electrocardiographic findings discovered at screening is quite different from when they arise in clinical practice. Among the 6 per cent of men in this study with patterns suggesting ischaemia, the subsequent coronary heart disease mortality was little more than 1 per cent per year; and among those who were symptom free it was even less.